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Contact Info
Dr. Debarshi Sarkar
9670534105
Department of Zoology, School of Basic Sciences, Central University of Punjab, VPO-Ghudda, Bathinda-151401
Dr. Debarshi Sarkar
Qualification
Qualification Organization Year Discipline
Ph. D. Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India 2012-2019 Zoology
M. Sc. Department of Zoology, University of North Bengal, WB, India 2007-2009 Zoology
B.Sc. Ananda Chandra College (University of North Bengal), WB, India 2004-2007 Zoology (Hons), Botany, Chemistry
Experience

Teaching and Research Experiences:-

 

1. Assistant Professor, Department of Zoology, School of Basic Sciences, Central University of Punjab, Bathinda, India (January, 2020-present).

 

2. SRF in an ICMR- sponsored project at Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India (2019-2020).

 

3. Worked as a Lecturer (Adhoc) at the Department of Zoology, Ananda Chandra College (University of North Bengal), West Bengal, India (2009-2012).

 

 

 

 

Research Area

Molecular Endocrinology and Reproductive Physiology

Research Interests

My research interests are focused on spermatogenesis and its regulation at anatomical, cellular and molecular level using mouse and/or rat as animal model.

I am actively engaged in evaluating reproductive toxicity of emerging environmental contaminants like brominated flame retardants (BFRs), which are potential threat to human health, using a combination of in vivo, in silico and molecular approaches to investigate as to how the male progeny responds to these contaminants after maternal exposure during lactation.

My research interest further lies in exploring the effect of neonatal hypothyroidism on male reproductive health especially in terms of glucose homeostasis in mouse testis and these experimental models illustrate the thyroid control of testicular differentiation and metabolism during development.

Recently, I am trying to elucidate the role of certain neuropeptides and cytokines in regulation of spermatogenesis.

Research Grants/Projects

1. Defining the role of Orexin B, a novel hypothalamic neuropeptide, in regulation of spermatogenesis in mouse model (2020-2022). Funded by: DST-SERB, India (Rs. 29,26000/-).

 

2. Chemical profiling and evaluation of antifertility potential of aqueous leaf extract of Allamanda cathertica L. in male laboratory mice (2021-2023). Funded by: RSM grant, Central University of Punjab (Rs. 3,00000/-).

Professional Affiliation

1. Life Member of the Indian Society for the Study of Reproduction and Fertility.

 

2. Member of the International Network for Young Researchers in Male Fertility.

Professional Recognition/Awards/Scholarships

2019

 

Prof. N. R. Moudgal Young Scientist Award by Indian Society for the Study of Reproduction and Fertility (ISSRF) for outstanding contribution in Reproductive Biology.

 

2017

 

Senior Research Fellowship from DST-PURSE, BHU, India

 

2016

International Travel Grant Award from DST-PURSE, BHU, India for oral presentation at 19th European Testis Workshop, Saint Malo, France.

2016

 

Prof. N. J. Chinoy Award from Society for Reproductive Biology and Comparative Endocrinology (SRBCE), India, for being second in oral presentation at ICIPCE-2016, BHU, Varanasi, India.

 

 

2015

 

Travel Grant Award from Society for Experimental Biology (SEB), London, UK for oral presentation at CEIP 2015, Trivandrum, Kerala.

 

2015

 

Best Poster Presentation Award at 25th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF) and International Conference on Reproductive Health, NIRRH, Mumbai, India.

 

2015

 

Best Poster Presentation Award at International Symposium on Reproductive Biology and Comparative Endocrinology, Banaras Hindu University, Varanasi, India.

 

2011

 

Qualified CSIR-UGC National Eligibility Test in June, 2011.

Research Collaboration

1. Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi-221005, India.

Publications

1. Sarkar, D., Singh, S.K., 2021. Decabromodiphenyl ether (BDE-209) exposure to lactating mice perturbs steroidogenesis and spermatogenesis in adult male offspring. Ecotoxicology and Environmental Safety. 209, 111783. (IF: 6.291)

 

2. Sarkar, D., Joshi, D., Singh, S.K., 2019. Maternal BDE-209 exposure during lactation causes testicular and epididymal toxicity through increased oxidative stress in peripubertal mice offspring. Toxicology Letters. 311, 66-79. (IF: 4.372)

 

3. Sarkar, D., Singh, V.K., Singh, S.K., 2018. Maternal BDE-209 exposure during lactation perturbs steroidogenesis, germ cell kinetics and THRα1 expression in testes of prepubertal mice offspring. Food and Chemical Toxicology. 122, 104-119. (IF: 6.023)

 

4. Joshi, D., Sarkar, D., Singh, S.K., 2018. The hypothalamic neuropeptide orexin A- a possible regulator in glucose homeostasis and germ cell kinetics in adult mice testes. Biochimie. 152, 94-109. (IF:4.079)

 

5. Sarkar, D., Singh, S.K., 2018. Inhibition of testicular steroidogenesis and impaired differentiation of Sertoli cells in peripubertal mice offspring following maternal exposure to BDE-209 during lactation suppress germ cell proliferation. Toxicology Letters. 290, 83-96. (IF: 4.372)

 

6. Joshi, D., Sarkar, D., Singh, S.K., 2017. Decreased expression of orexin 1 receptor in adult mice testes during alloxan-induced diabetes mellitus perturbs testicular steroidogenesis and glucose homeostasis. Biochemical and Biophysical Research Communications. 490, 1346-1354. (IF: 3.575)

 

7. Sarkar, D., Singh, S.K., 2017. Maternal exposure to polybrominated diphenyl ether (BDE-209) during lactation affects germ cell survival with altered testicular glucose homeostasis and oxidative status through down-regulation of Cx43 and p27Kip1 in prepubertal mice offspring. Toxicology. 386, 103-119. (IF: 4.221)

 

8. Sarkar, D., Singh, S.K., 2017. Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43. Andrology. 5, 749-762. (IF: 3.842)

 

9. Sarkar, D., Singh, S.K., 2017. Effect of neonatal hypothyroidism on prepubertal mouse testis in relation to thyroid hormone receptor alpha 1 (THRα1). General and Comparative Endocrinology. 251, 109-120. (IF: 2.822)

 

10. Sarkar, D., Chowdhury, J.P., Singh, S.K., 2016. Effect of polybrominated diphenyl ether (BDE-209) on testicular steroidogenesis and spermatogenesis through altered thyroid status in adult mice. General and Comparative Endocrinology. 239, 50-61. (IF: 2.822)

 

11. Sarkar, D., Singh, S.K., 2016. Polybrominated diphenyl ethers: effect on male reproductive health as thyroid hormone disruptors. ISSRF Newsletter. 18, 19-23.

 

 

Research Guidance

M.Sc.:- 04
Ph.D.:- 01 (Ongoing) (Riyaz Ahmad; CSIR-UGC-JRF)

Conference/ Workshops/Seminars Attended

Training course/ workshop attended:-

 

1. Participated (as a trainee) in Two Weeks Workshop on “Basic and Advanced Proteomics Approaches” organized by IIT Bombay from 15th to 26th February, 2021, sponsored by Department of Science and Technology, Govt of India.

 

2. Participated (as a trainee) in One Week Workshop on “Sequence Analysis, Molecular Modeling and Docking (SAMMD) 2016” organized by Department of Biotechnology, Banaras Hindu University, Varanasi, India, from 9th to 15th March, 2016.

 

3. Participated (as a trainee) in Two Weeks Training Course on “Application of Research Techniques in Reproductive Biomedicine’’ organized by National Institute of Health and Family Welfare, New Delhi, India, from 29th October to 9th November, 2012.

 

Conference/ seminars attended:-

Oral presentations

 

1. International Conference on Frontiers in Comparative Endocrinology and Neurobiology, University of Hyderabad, Hyderabad, India (25th - 28th November, 2014).

 

2. International Symposium on Comparative Endocrinology and Integrative Physiology, Central University of Kerala, Trivandrum, India (4th - 7th August, 2015).

 

3. 34th Annual Meeting of the Society for Reproductive Biology and Comparative Endocrinology (SRBCE) and International Symposium on Integrative Physiology and Comparative Endocrinology (ISIPCE-2016), Banaras Hindu University, Varanasi, India (12th - 14th February, 2016).

 

4. 26th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF) and International Conference on Reproductive Health with Emphasis on Occupational, Environmental and Lifestyle factors. NIOH, Ahmedabad, India (18th - 20th February, 2016).

 

5. 19th European Testis Workshop. Saint Malo, France (11th - 15th June, 2016).

 

Poster presentations

 

1. National Symposium on Recent Advances in Reproductive Health, Banaras Hindu University, Varanasi, India (28th - 30th November, 2013).

 

2. 24th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF) and International Conference on Reproductive Health: Issues and Strategies under Changing Climate Scenario, IVRI, Izatnagar, UP, India (6th - 8th February, 2014).

 

3.  25th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF) and International Conference on Reproductive Health, NIRRH, Mumbai, India (14th - 17th February, 2015).

 

4. International Symposium on Reproductive Biology and Comparative Endocrinology, Banaras Hindu University, Varanasi, India (25th - 27th February, 2015).

 

5. 27th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF) and International Conference on Reproductive Health with Emphasis on Strategies for Infertility, Assisted Reproduction and Family Planning, AIIMS, New Delhi, India (23rd - 25th January, 2017).

 

Conference/ Workshops/Seminars Organised
University Level
 
National Level
 
International Level

 

Peer Recognition

1. Reviewer of Journal: Andrologia (ISSN: 1439-0272; Publisher: Wiley Blackwell)

Invited Talks/ Resource Person
1. Resource person in One Week Workshop on “Advances and Applications of Proteomics in Endocrinology” organized by Department of Zoology, Banaras Hindu University, Varanasi, India, from 17th to 23rd November, 2018.
Citations

Citations:158

h-index:7

i-10 index: 7

Other Significant Achievements

Data from my four publications (PMID:28572024; PMID:26602377; PMID:30300726; PMID:29578053) have been incorporated in comparative toxicogenomics database (CTD), one of the largest databases in the field of toxicology run by Department of Biological Sciences at North Carolina State University and supported by the National Institute of Environmental Health Science (NIEHS), USA that aims to explore how environmental exposures affect human health.