Dr. Monisha Dhiman

Contact Info
Dr. Monisha Dhiman
8146565969
Dr. Monisha Dhiman

Professor and Head
Department of Microbiology
School of Basic Sciences

Qualification

INSTITUTION AND LOCATION

DEGREE

(if applicable)

YEAR(s)

FIELD OF STUDY

University of Texas Medical Branch, Galveston, TX, USA

University of Texas Medical Branch, Galveston, TX, USA

Himachal Pradesh University, Shimla and  Jawaharlal Nehru University, New Delhi, India

Himachal Pradesh University, Shimla, and Jawaharlal Nehru University, New Delhi, India

Himachal Pradesh University, Shimla, India

St Bede’s college, Shimla, India

 

Research Scientist-I

Postdoctoral Fellow

Ph.D

M.Phil.

M.Sc

B.Sc

 

Nov. 2010-May 2012

2006- Oct. 2010

2002-06

2000-02

1998-00

1995-98

Oxidative stress response networks in human Chagasic cardiomyopathy

Trypanosoma cruzi  Induced Oxidative Stress

Immunology

Radiation and Cancer Biology

Radiation and Cancer Biology

Zoology (Specialization in Radiation and Cancer Biology)

Zoology, Chemistry and Botany
Experience
Teaching Experience: 

04 Jan 2019-till date: Head, Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India

14 Jan 2020-Till date: Professor (Direct Recruitment), Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India

28 Dec 2018- 13 Jan 2020:  Professor (Career Advancement Scheme), Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India

28 Dec 2015-27 Dec 2018: Associate Professor, Department of Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, Punjab, India

01 July 2013-27 Dec 2015:  Assistant Professor, Centre for Genetic Diseases and Molecular Medicine, Central University of Punjab, Bathinda, Punjab, India

31 May 2012-June 2013: Assistant Professor, Centre for Biosciences, Central University of Punjab, Bathinda, Punjab, India

 

Research Experience: 

May 2012- till date: Involved in research by guiding Masters, MPhil, PhD students and by utilizing various extramural grants.

 

01 Nov 2010- 25 May 2012: Research Scientist-I, Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA

24 April 2006-31 Oct 2010     Postdoctoral Research Fellow, Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA

Administrative Experience:
  1. Head, Dept.of Microbiology (July 2019-till date)
  2. Head, Dept.of Biochemistry and Microbial Sciences (January 2019-June 2019)
  3. Member, Academic Council , Central University of Punjab, Bathinda.
  4. Member, Internal Complaint Committee
  5. Member, Institutional Ethics Committee
  6. Member, IQAC
  7. Member, Library Advisory committee
  8. President, Institution Innovation Council (IIC, MHRD)
  9. Nominated by Institutional Innovation Council to attend the Orientation of IIC-2 and ARIIA -regional mentoring session on 19th July, 2019 in Punjab Engineering College, Chandigarh, organized by MHRD’s Innovation Cell.
  1. Convener, Institution Innovation Council (IIC, MHRD) (2018-2020). Represented university at the inaugural function of the launch of IIC at AICTE HQs, New Delhi on 21 November, 2018.
  2. Convener, Institutional Biosafety Committee (IBSC)
  3. Represented Central University of Punjab in “Festival of Innovation” at Rashtrapati Bhawan, March 8, 2017
  4. Academic and Administrative Committee of the Centre : Convener (2015-2019)
  5. Academic and Administrative Committee of the Centre : Chair (2019 onwards)
  6. Board of Studies: Member
  7. School Board Member:  Member
  8. School Admission Committee:  Member Secretary
  9. Editorial Board Newsletter
  10. Earn While you Learn Scheme (Coordinator)
  11. Community Development Cell /Unnat Bharat Abhiyaan: Nodal officer
  12. Mess Advisory Committee
  13. NSS Programme officer (April 2016-2019) NSS: Programme Coordinator (From April 2019 )
  14. Member, Rashtriya Avishkaar Abhiyaan
  15. Member, International Collaboration Cell
  16. Faculty Advisor: Vardaan Club
  17. Annual Report Committee
  18. Room allotment Committee
  19. Day Care Centre: Member (September, 2012-May, 2018)
Any Other Experience

 

Research Area

My focus of research is to know whether ROS/RNS induced oxidative stress activates innate defense response during carcinogenesis and role of antioxidants in this regard. My ultimate goal is to delineate the complex interrelationships between the oxidative stress and inflammatory mediators, wherein the promise of antioxidant and anti-inflammatory therapies in controlling progressive disease conditions can be realized. Currently, I have following work undergoing or in pipeline:
    Inflammation and its molecular and cellular targets during H. pylori infection and associated gastric cancer. 
    Evaluating the mechanism involved in the toxicity of Anthracyclines used as chemotherapeutic drugs (DST funded).
    Development plasma/serum proteome with reference to the specific biomarkers of oxidative/nitrosative stress produced during the course of carcinogenesis and analysis for the identification of tumor-associated biomarkers.
    Serological studies to investigate the diagnostic and prognostic efficacy of the bio-markers of inflammation, oxidative stress and antioxidant status of human diseases such as cancer, diabetes and chronic heart diseases.
    To investigate the cause effect relationship between the environmental contaminants and hypertension and diabetes  in Malwa region of Punjab. 

Research Interests

Trained in proteomics and disease-state specific bio markers analysis at University of Texas Medical Branch, Galveston (USA). Expertise include maintaining parasite, cell lines, handling/caring mouse colonies (knock-out, transgenic), cutting-edge molecular approaches, oxidative biochemistry and enzymology, inflammatory pathology.

Research Grants/Projects

A. Project as Principal Investigator (Completed)
Title: Chemotherapeutic Drug Induced Cardiomyocyte Toxicity: Evaluation of Ethno-Botanical Plants to  
     Minimize the Cardiac Damage.
Funding Agency: Dept. of Science and Technology (DST) Fast Track, Rs 23 Lakhs

B.    Project as Co - Principal Investigator (Completed)
Principal Investigator: Dr. Anil K. Mantha
Title: Mitochondrial Oxidative DNA Damage-Repair in Alzheimer’s disease: AP-endonuclease (APE1/Ref-1) as a Potential Therapeutic Target.
Funding Agency: Dept. of Science and Technology (DST), New Delhi, Rs. 46 Lakhs

C.    Project as Principal Investigator (completed)
Title: Molecular Mechanisms of Pollen-Mediated Stress in Human Epithelial Lung cell line.
Funding Agency: Central University of Punjab, Bathinda as Research Seed Money. Rs. 3 Lakhs for 2 years (2014-16).

D.    Unnat Bharat Abhiyaan (Co-investigator)  1.75 lakhs, 2017-2019

Professional Affiliation

Life member of Indian Immunology Society
2013- till date           Editorial Board Member, J. of Cell Sci. and Mol. Bio
2010-till date             American Society of Tropical Medicine and Hygiene (ASTMH) 
2010-till date        International Society for Infectious Diseases (ISID)
2010-till date        International Society for Heart and Lung Transplant (ISHLT)
2009                  Certified for teaching and mentoring (Bromberg workshop in teaching and mentoring at UTMB, Galveston)
2008-till date      American Society for Microbiology
2007-till date        Society for Free Radical Biology and Medicine
2007            American Heart Association
2006           Certified “Basic Radiation Safety in the Laboratory”. University of Texas Medical   Branch, Galveston, Texas, USA
 

Professional Recognition/Awards/Scholarships

2020:  Nominated as Member of the Advisory Committee for Year of Awareness on Science & Health (YASH) Programme constituted by National Council for Science & Technology Communication (NCSTC) and Dept. of Science and Technology (DST), Govt. of India.

2019: Award of Excellence for Brilliant and consistent high standards of workmanship in the field of scientific research, from Bank of India on International Women’s Day, 08 March 2019.

2019:   Recipient of Faculty Research Award from Central University of Punjab, Bathinda on 10th Foundation Day under the category cumulative Impact Factor more than 15 of research publications in the academic year (2017-18). 

2019:   Recipient of Outstanding Researcher Award from Central University of Punjab, Bathinda on 10th Foundation Day.

2017:    Prof AR Rao Memorial Young Scientist Award from Society for Mitochondrial Research and Medicine (SMRM) organized by the Jawaharlal Nehru University (JNU), New Delhi, India 10-11, February 2017.

2017:    Merit certificate for commendable work in Community Development Cell on 8th Foundation Day of Central University of Punjab, Bathinda.
2013:     SERB, Young Investigator Award, DST
2012      Judge at Galveston County Science Fair at Moody Gardens Convention Center, Galveston, USA.
2011      Facilitator for the small group discussion for the Cell Biology course for medical students. 
             UTMB, Galveston, USA.
2011      Judge at Medical Student Summer Research Program (MSSRP), UTMB, USA
2010      Second prize for oral presentation in National Postdoc Appreciation Week, symposium at UTMB,  Galveston, USA.
2009     First prize in poster presentation in ‘’International Education Week” organized by PAHO/WHO Collaborating Center for Training in International Health at UTMB, Galveston, USA.
2008       Travel award through the Burroughs Wellcome Trust to attend the 108th General Meeting, American Society for Microbiology, Boston, Massachusetts, USA. 
2004-2006    Council for Scientific and Industrial Research (CSIR)/UGC- Senior Research Fellowship, New Delhi, India
2002-2004    Council for Scientific and Industrial Research (CSIR)/UGC- Junior Research Fellowship, New Delhi, India

Research Collaboration

Dept of Zoology, Central University of Punjab, Bathinda 

Dept of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda 

Dept. of Environmental Sciences and Technology, Central University of Punjab, Bathinda 

Publications

Research Paper and reviews:

1.  Verma H, Cholia RP, Kaur S, Dhiman M, Mantha AK. A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme. Metab Brain Dis. 2021 Jun;36(5):751-765. doi: 10.1007/s11011-021-00690-y. Epub 2021 Mar 2. Impact Factor (IF): 4.41

2. Gupta KB, Mantha AK, Dhiman M (2021) Mitigation of Gliadin-Induced Inflammation and Cellular  Damage by Curcumin in Human Intestinal Cell Lines. Inflammation. 2021 Jan 4. doi: 10.1007/s10753-020-01383-x. Online ahead of print.PMID: 33394186. Impact Factor (IF): 3.22 3.    Shishir Upadhayay, Kunj Bihari Gupta Anil K Mantha and Dhiman M (2020).  A short review:  Doxorubicin and its effect on cardiac proteins. Journal of Cellular Biochemistry.  2020 Sep 14. doi: 10.1002/jcb.29840. [IF= 4.22].  4.    Thakur S, Sarkar B, Dhiman M, Mantha AK. Organophosphate-pesticides induced survival mechanisms, and APE1-mediated Nrf2 regulation in non-small cell lung cancer cells. J. of Biochemical and Molecular Toxicology.  2020 Oct 20:e22640. [IF=3.66].  5.    Mandeep Kaur#, Kunj Bihari Gupta#, Shweta Thakur#, Sukhchain Kaur, and Dhiman M. (2020) Parthenium hysterophorus Mediated Inflammation and Hyper-responsiveness via NF-κB Pathway in Human A549 Lung Cancer Cell Line. Environmental Toxicology Nov;35(11):1241-1250.  [IF=3.11]. 6.    Shishir Upadhayay, Anil K Mantha and Dhiman M (2020).  Glycyrrhiza glabra (Licorice) Root Extract Attenuates Doxorubicin-Induced Cardiotoxicity via Alleviating Oxidative Stress and Stabilising the Cardiac Health in H9c2 Cardiomyocytes. Journal of Ethnopharmacology, Jan 2020. (IF): 3.4 7.    Shishir Upadhayay, Nidhi Sharma Anil K Mantha and Dhiman M (2019). Anti-Cancer Drug Doxorubicin Induced Cardiotoxicity: Understanding the Mechanisms Involved Through ROS Generation Resulting in Mitochondrial Dysfunction. RASAYAN Journal of Chemistry. January 2020, 13(2): 1042-1053 (IF:1.22) 8.    Kumar S and Dhiman M. (2018) Inflammasome activation and regulation during Helicobacter pylori pathogenesis. Microbial  Pathogenesis. Dec; 125: 468-474. doi: 10.1016/j.micpath.2018.10.012. Epub 2018 Oct 10. Review. (IF): 2.33.

9.    Upadhyay, S., Vaish S., Dhiman, M. (2019) Hydrogen Peroxide Induced Oxidative Stress and its Impact on Innate Immune Responses in Lung Carcinoma A549 Cells. Mol Cell Biochem.  Jan; 450(1-2):135-147. (IF): 2.66.

10.    Cholia RP, Dhiman M, Kumar R, Mantha AK (2018). Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes. Metabolic Brain Disease. Aug;33 (4):1307-1326. (IF): 2.63.

11.    R. Kaur, Rubal, Raja Paramjeet Singh Banipal, Rajesh Vashistha, Monisha Dhiman and Anjana Munshi. (2019) Association of elevated levels of C-reactive protein with breast cancer, breast cancer subtypes and poor outcome. Current Problems in Cancer.  Apr; 43(2):123-129. (IF): 1.66.

12.    Singla, R., Gupta, K. B., Upadhyay, S., Dhiman, M., & Jaitak, V. (2018) Design, Synthesis and Biological Evaluation of Novel Indole-Benzimidazole hybrids Targeting Estrogen Receptor Alpha (ER-α), European Journal of Medicinal Chemistry, 146: 206-219.  (IF): 4.35.

13.    Singla, R., Gupta, K. B., Upadhyay, S., Dhiman, M., & Jaitak, V. (2018)  Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators.  Bioorganic & Medicinal Chemistry 26 (1): 266-277. (IF): 2.79

14.    Upadhyay, S., Sharma N., Gupta, K.B., Dhiman, M. (2018) Role of Immune System in Tumor Progression and Carcinogenesis. Journal of Cellular Biochemistry Jul; 119(7): 5028-5042.        (IF): 4.2

15.    Gupta, K.B., Upadhyay, S., Saini, R. G., Dhiman, M. (2018) Inflammatory Response of Gliadin Protein Isolated from Various Wheat Varieties on Human Intestinal Cell Line. Journal of Cereal Science, 81: 91-98, (IF): 2.65

16.    R. Kaur, Rubal, Dhiman, M., Vashitstha R., Munshi A. (2017) Serum Albumin Levels in Breast Cancer: Correlation with Overall Survival. J Food Nutr Disor, 6:5-15.

17.    Singla R, Prakash K., Gupta KB, Upadhyay S, Dhiman M, & Jaitak V  (2018).  Identification of novel indole based heterocycles as selective estrogen receptor modulator. Bioorganic Chemistry, 79: 72–88. (IF): 3.92

18.    Thakur S, Dhiman M, Mantha AK (2018). APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells.  Mol Cell Biochem.  441(1-2):201-216.  (IF): 2.66

19.    Sarkar B, Dhiman M, Mittal S, Mantha AK. (2017). Curcumin revitalizes Amyloid beta (25-35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and Nrf2. Metab Brain Dis. 32(6):2045-2061.   (IF): 2.63.

20.    Cholia RP, Kumari S, Kumar S, Kaur M, Kaur M, Kumar R, Dhiman M, Mantha AK. (2017 )An in vitro study ascertaining the role of H2O2 and glucose oxidase in modulation of antioxidant potential and cancer cell survival mechanisms in glioblastoma U-87 MG cells. Metab Brain Dis. Oct;32(5):1705-1716. doi: 10.1007/s11011-017-0057-6.  (IF): 2.63

21.    Gill, Iqbal,  Kaur, Sukhchain, Kaur, Navrattan, Dhiman, M., Mantha, Anil K. (2017) Phytochemical Ginkgolide B attenuates Aβ(1-42)- induced oxidative damage and altered cellular responses in human neuroblastoma SH-SY5Y cells. Journal of Alzheimer’s Disease; 60(s1):S25-S40. Impact Factor (IF): 4.1.

22.    María Zago, Yashoda Hosakote, Sue-jie Koo, Dhiman M, María Piñeyro, Adriana Parodi-Talice, Miguel Basombrio, Carlos Robello, and Nisha Garg (2016) TcI isolates of Trypanosoma cruzi exploit antioxidant network for enhanced intracellular survival in macrophages and virulence in mice.  Infection and Immunity. May 24;84(6):1842-56. (IF): 3.74                                                                                                                      23.    Dhiman M*, and Garg N. J, (2014) P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection. PLOS Pathogens Dec 4;10(12):e1004516. doi: 10.1371/journal.ppat.1004516.     (IF): 8.2.                                                                                                      

24.    Kaur N, Dhiman M, Perez-Polo, JR, and Mantha AK (2015) Ginkgolide B Revamps Neuroprotective Role of APE1 and Mitochondrial OXPHOS Against Aβ(25-35)-Induced Neurotoxicity in Human Neuroblastoma Cells. Journal of Neuroscience Research.  Jun;93(6):938-47.    (IF):  2.99                                                            

25.    Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK. (2014) APE1/Ref-1 as an Emerging Therapeutic Target for Various Human Diseases: Phytochemical Modulation of its Functions. Experimental Molecular Medicine. 2014. Jul 18; 46: e106. doi: 10.1038/emm.2014.42.                                                                                      (IF): 5.16 26.    Thakur S, Dhiman, M, Tell G, and Mantha AK. (2015) A Review on Protein-Protein Interaction Network of APE1/Ref-1 and its Associated Biological Functions Cell Biochemistry & Function. 2015 Apr;33(3):101-12. doi: 10.1002/cbf.3100. Epub 2015 Mar 19.         (IF): 2.134            

27.    Dhiman M., Wan X., Popov V. L., Vargas G., Garg N. J. (2013) MnSODtg Mice Control Myocardial Inflammatory and Oxidative Stress and Remodeling Responses Elicited in Chronic Chagas Disease. Journal of American Heart Association 2 (5): e000302.  (IF):  4.36                                                                                      

28.    Dhiman M, Coronado YA, Vallejo CK, Petersen JR, Ejilemele A, Nuñez S, Zago MP, Spratt H, Garg NJ. (2013) Innate immune responses and antioxidant/oxidant imbalance are major determinants of human Chagas disease. PLoS Negl Trop Dis. Aug; 7(8):e2364.     (IF):  4.8        

29.    Eaves-Pyles T, Patel J, Arigi E, Cong Y, Cao A, Garg N, Dhiman M, Pyles RB, Arulanandam B, Miller AL, Popov VL, Soong L, Carlson E, Coletta C, Szabo C, Almeida I. (2013) Immunomodulatory and anti-bacterial effects of cystatin-9 against F. tularensis. Mol Med. Aug 2. doi: 10.2119/molmed.2013.00081.                                  (IF):  5.1

30.    Gupta S, Wan X., Zago M. P,  Martinez Sellers V,  Silva T S, Assiah D, Dhiman M, Nuñez S, Petersen   J R, Vázquez-Chagoyán J, Estrada-Franco J G, Garg N J. (2013) Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease. PLoS Negl Trop Dis 2013; 7(1):e2018           (IF): 4.8       

31.    Mantha AK, Dhiman M, Taglialatela G, Perez-Polo RJ, Mitra S. (2012) Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction. J Neurosci Res. Jun; 90(6):1230-9. (IF): 2.99.                                                                                                                         

32.    Dhiman M, Paola M. Zago, Sonia Nunez, Federico Nunez-Burgio and Nisha Jain Garg. (2012) Cardiac-oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis. PLoS One 7; (1):e28449.                                                                                           (IF): 3.8

33.    Dhiman M and Garg NJ. (2011) Inhibition of NADPH-oxidase Attenuates T cruzi-induced Cardiac Pathology.  Journal of Pathology (2011) Dec; 225(4):583-96. (IF): 7.2  

34.    Jose´ E. Aparicio-Burgos, Laucel Ochoa-Garcıa, Jose´ Antonio Zepeda-Escobar, Shivali Gupta, Monisha Dhiman, Jose´ Simon Martınez, Roberto Montes de Oca-Jimenez, Margarita Val Arreola, Alberto Barbabosa-Pliego, Juan C. Vazquez-Chagoyan, Nisha Jain Garg (2011). Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs. PLoS Negl Trop Dis  5(5): 1-10.                                 (IF):  4.8   

35.    Wen J-J, Gupta S, Guan Z, Dhiman M, Condon D, Lui CY, Garg NJ (2010). Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats. J Amer College Cardiology. 2010, 55(22):2499-508.                                                     (IF): 19.89                                                                         

36.    Dhiman M, Jasmine Pando, Estrada-Franco JG, Aguilar FR, Corzo SB, Perez GM, Sandoval RG, Garg NJ. (2009) Increased myleoperoxidase activity and protein nitration are indicators of inflammation in chagasic patients. Clinical and Vaccine Immunology, 16(5):  660-666.                  (IF):3.08                                                                                                                  37.    Dhiman M, Nakayasu ES, Hosakote YM, Reynolds BK, Wen JJ, Almeida IC and Garg NJ. (2008) Enhanced Nitrosative Stress during Trypanosoma cruzi Infection Causes Nitrotyrosine Modification of Host Proteins. Implications in Chaga’s disease.  Am J Pathol.  173 (3): 728-740                                                       (IF): 6.34

38.    Wen J-J#, Dhiman M#, and Garg NJ. (2008) Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice. Microbes Infect.  10 1201-1209. #Equal Contribution         (IF): 3.0                                                          

39.    Deep G, Dhiman M, Mendiz E, Rao AR and Kale RK. (2005) Chemo preventive Effects of Mustard Seeds in Chemically Induced Fore stomach and Uterine Cervix Tumors in Murine Model System. Human & Experimental Toxicology. 24 (6): 303-312.    (IF): 2.78                                                                                                                                                     40.    Deep G, Dhiman M, Rao AR and Kale RK. (2005). Chemopreventive Potential of Triphala on Benzo(a)Pyrene Induced Forestomach Tumorigenesis in Murine Tumor Model System. Journal of Experimental & Clinical Cancer Research.  24 (4) 555-563.      (IF): 6.2                                                                                                                                                     41.    Dhiman M, Malhotra N and Kale RK. (2004) Quercetin as a radiomodulator. Indian Journal of Radiation Research. 1(2): 18-19.   # Equal contribution           

Publications in Conference Proceedings            

  1. M Dhiman and  NJ Garg (2015) NADPH-Oxidase an essential enzyme for the expansion and activation of CD8+ T cells during Trypanosoma cruzi infection. American Journal of Tropical Medicine and Hygiene 93 (4), 537. (IF): 2.57                                                                                        
  2. NJ Garg and M Dhiman (2010) NADPH-Oxidase: Role in Progression of Myocarditis during Trypanosoma cruzi Infection and Chagas Disease. Free Radical Biology and Medicine 49, S142.             (IF): 5.75                                                                                       
  3. M Dhiman and NJ Garg (2010). Activation of NADPH-Oxidase-reactive oxygen species-inflammatory cytokines pathway contribute to acute myocardial pathology in mice infected by Trypanosoma cruzi. American Journal Of Tropical Medicine and Hygiene 83 (5), 381. (IF): 2.57                                                                                        
  4. M Dhiman, E Nakayasu, YM Hosakote, RK Brobey, J Wen, IC Almeida, NJ Garg (2007). Development of Nitrosyl-plasma Proteome in Chagas Disease: Identification of Novel Diagnostic Biomarkers.  Free Radical Biology and Medicine 43, S164.   (IF): 5.75                                                                                       
  5. M Dhiman, J Pando, JG Estrada-Franco, F Ramirez-Aguilar, NJ Garg  (2007) Myeloperoxidase Activation and Increased Protein Nitration/oxidation in Chagasic Patients. Free Radical Biology and Medicine 43, S45-S46. (IF): 5.75 

Book chapters

  1. Sharanjot Kaur, Kunj Bihari Gupta, Sandeep Kumar, Anil K. Mantha and Dhiman M. (2021)Methods to Detect Nitric Oxide and Reactive Nitrogen Species in Biological Sample. Cancer Biomarkers: Methods and Protocols, Springer publisher.
  2. Kunj Bihari Gupta, Sharanjot Kaur, Dhiman M and Anil K. Mantha. (2021) Methods to assess oxidative DNA base damage repair of apurinic/apyrimidinic (AP) sites using radioactive and non-radioactive oligonucleotides based assays. Cancer Biomarkers: Methods and Protocols, Springer publisher.
  3. Shishir Upadhyay, Kunj Bihari Gupta, Sukhchain Kaur, Rubal, Sandeep Kumar, Anil K. Mantha and Dhiman M*(2018). Resveratrol: A Miracle Drug for Vascular Pathologies Functional Foods and Human Health. Springer Publishers. Pages 119-142

  4. Kaur S, Dhiman M, and Mantha AK (2018). Ferulic Acid: A Natural Antioxidant with Applications toward Neuroprotection against Alzheimer’s disease. Functional Foods and Human Health. Springer Publishers. Pages 575-586

  5. Dhiman M*,Thakur S, Upadhyay S, Kaur A and Mantha A K (2014) “Oxidative Stress and Inflammation in Cardiovascular Diseases: Two Sides of the Same Coin”. Free Radicals in Human Health and Disease, Oxidative Stress and Human Health. Springer Publishers. Pages 259-278. Print ISBN978-81-322-2034-3 Online ISBN978-81-322-2035-0.

  6. Kaur N, Sarkar B, Mittal S, Dhiman M, Taglialatela G, Perez-Polo R.J., Mantha AK. (2014) “Oxidative Stress Events and Neuronal Dysfunction in Alzheimer’s Disease: Focus on APE1/Ref-1 Mediated Survival Strategies.” Free Radicals in Human Health and Disease, Oxidative Stress and Human Health. Springer Publishers. Pages 175-207

  7. Gupta S, Dhiman M, Wen JJ, Garg NJ. ROS signaling of inflammatory cytokines during T. cruzi infection.  Advances in Parasitology (2011) 76:153-70.   Edited by Louis M. Weiss, Herbert B. Tanowitz. (IF): 6.00.                                                                                  

Research Guidance
  1.  Ph.D. Guidance

    Sl. No.

    Name of Scholar

    Title of Thesis

    Name of Department & University Guided

    Date of Award

    1

    Dr. Shweta Thakur#

    A Biochemical Study to Evaluate the Role of Apurinic/Apyrimidinic Endonuclease 1 (APE1) in Lung Cancer Progression

    Biosciences, CUPB

    March 2018

    2

    Dr Shishir Upadhyay*

    In-Vitro Study to Evaluate the Effect of Viola Pilosa and Glycyrrhiza Glabra Extracts on Doxorubicin Induced Cardiotoxicity in H9c2 Cardiomyocytes

    Biosciences, CUPB

    Nov 2020

    3

    Dr Kunj Bihari Gupta**

    Influence of Wheat Protein Gliadin on Oxidative Stress, Inflammation and Associated Signaling Pathways in Human Intestinal Cells

    Biochemistry and Microbial Sciences

    May 2021

# Dr. Shweta Thakur was awarded prestigious DST-NPDF in 2019

*Shishir Upadhyay awarded best PhD Research Scholar by Central University of Punjab, Bathinda on 9th Foundation Day, 2018.

**Kunj Bihari Gupta awarded best PhD research scholar by Central University of Punjab, Bathinda on 10th Foundation Day, 2019.

Conference/ Workshops/Seminars Attended
University Level
 
National
 
International

 

Conference/ Workshops/Seminars Organised
University Level
 
National Level
 
International Level

 

Invited Talks/ Resource Person
Resource Person:
1.Served as Resource person in Motivational Contact Programme for Talented School Students of Punjab, 14 to 18 September 2015.
2. Served as Resource person in a Refresher course conducted by Centre for Plant Sciences from February 01 to 15 February 2016.
3. Served as Resource person in DBT-Sponsored Training Course in Medical Genetics and Bioinformatics organized by Centre for Human Genetics and Molecular Medicine, March 2016
4. Served as Resource person in Department of Biotechnology and Medical Sciences, Baba Farid College, Bathinda, Punjab, in Innovation in Science Pursuit for Inspire Research (INSPIRE) Internship Science Camp under the INSPIRE Internship Program, Department of Science and Technology (DST), New Delhi, 27th December, 2018.
5. Resource person for a session and moderator for session by Padma Sri Prof. Dipankar Chatterji (Fellow of all science academies, Winner of Bhatnagar Award, ex-President of Indian Academy of Sciences, Bangalore) in Science-Academies'-INYAS " Science Leadership Workshop", held on June 22 to June 28 2020.
Invited Talks:
1. Invited online lecture in National Webinar on “Preparedness For Career Prospects During And Post Covid-19” organized by Placement Cell, Palamuru University, Telangana on 21st August 2020.
2. Invited online lecture on “T and B Cells receptors, their activation & functions: Key Player of Adaptive Immunity”on 01 May 2020 for the students of Department of Biotechnology, Faculty of Sciences, Baba Farid College, Bathinda.
3. Invited lecture on “Glycyrrhiza glabra root extract attenuates Doxorubicin-induced cardiotoxicity via regulating lipid homeostasis and cardiac metabolism through SIRT-1 Pathway” in 3th International Symposium on Cancer Prevention and Treatment February 20-21, 2020 School of Life Sciences, Jawaharlal Nehru University, New Delhi
4. Invited presentation on “Helicobacter pylori Pathogenesis: Role of Inflammasome Activation and Regulation” in 60th Annual Conference of “Association of Microbiologists of India (AMI-2019)” and International Symposium on “Microbial Technologies in Sustainable Development of Energy, Environment, Agriculture and Health” organized by Central University of Haryana, Mahendergarh, November 15-18, 2019.
5. Invited lecture on “Hydrogen Peroxide Induced Oxidative Stress and its Role in Innate Immune Responses in A549 Lung Carcinoma Cells” in International Symposium on “Tumor Microenvironment and Cancer Prevention & Therapeutics” organized by the Jawaharlal Nehru University (JNU), New Delhi, India during 08-09 February 2019.
6. Expert lecture on “Heavy Metal Induced Stress Responses and Defense Mechanisms in Living organisms” in DAV College, Abohar on 02 November, 2018.
7. Expert lecture on “Recent Trends and Innovations in the field of Science” in the 4th National Workshop on Innovations in Science-2018, organized by Yadavindra College of Engineering, Punjabi University Guru Kashi Campus on 16 October, 2018.
8. Guest lecture on “Beneficial Effects of Glycyrrhiza glabra Extract in Doxorubicin-Induced Cardiotoxicity via Stabilising and Restoring the Mitochondrial Redox functions at International Symposium on Cancer Treatment and Prevention organized by the Jawaharlal Nehru University (JNU), New Delhi, India 09-10 February 2018.
9. Expert lecture on “Novel Approaches in Research for Agriculture and Biotechnology” in Faculty Development programme at Baba Farid College, 17 January, 2018.
10. Invited lecture on “Role of Medicinal Plant Extracts On Doxorubicin-Induced Cardiotoxicity” at 6th International Conference on “Mitochondria in Health and Disease” of Society for Mitochondrial Research and Medicine-India (SMRM) organized by the Jawaharlal Nehru University (JNU), New Delhi, India 10-11 February 2017.
11. Invited talk on “Role of Mitochondria in Doxorubicin Induced Cardiotoxicity” at International Conference on Current Trends in Biotechnology” organised by Vellore Institute of Technology, Vellore from December 8-10, 2016
12. Expert Lecture on “Trends in Immuno-technology: B and T- Cells Mechanisms and Experimental Advances”. Baba Farid Group of Institutions, Dept. of Biotechnology, Bathinda, 22 September, 2016.
13. Invited talk on Chemotherapeutic Drug Induced Cardiomyocyte Toxicity: Evaluation of Ethno-Botanical Plants to Minimize the Cardiac Damage. International Symposium on Role of Herbs in Cancer Prevention and Treatment” held at School of Life Sciences, Jawaharlal Nehru University, New Delhi, Feb. 9 - 11, 2016.
14. Expert Lecture on “Recent Advances in Immunology and Molecular Biology: A Practical Approach”. Baba Farid Group of Institutions, Dept of Biotechnology, Bathinda, 28 September, 2015

Patent Filed/ Published
PATENT FILED
 
 
PATENT PUBLISHED
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Nodal Officer Community Development Cell
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